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Probiotic mixture VSL#3 prevents ulcerative colitis-associated carcinogenesis in mice and cells by regulating the inflammatory and Wnt/-catenin pathway

In this issue, we examine several significant FDA regulatory developments shaping clinical practice and pharmaceutical oversight

Hyponatraemia : SSRIs like fluoxetine can cause hyponatraemia (low sodium levels), particularly in older adults or those taking diuretics

Clinical trials show gastrointestinal side effects (nausea, vomiting, constipation) affect 20-40% of users across semaglutide, tirzepatide, and retatrutide, but severity and persistence vary widely

Semaglutide prescriptions, including Ozempic, have also been linked to other health issues, including: Thyroid tumors Diabetic retinopathy Acute kidney injury Increased heart rate Hyperglycemia (high blood sugar) Agitation, irritability, and other abnormal behaviors Stomach paralysis and other gastrointestinal conditions Gallstones The gallbladder stores bile produced by the liver, which aids in digestion