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[1] [2] Tirzepatide works by mimicking two naturally occurring incretin hormones that regulate appetite and glucose metabolism

Furthermore, a real-world retrospective study comparing the compliance of patients receiving different GLP-1RAs for the treatment of hyperglycemic found that even if GLP-1RA weekly preparations were used, there were still differences in compliance [171]

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In dose-response experiments, the 5 mg/kg dose group showed significantly reduced food intake, while the 20 mg/kg group nearly completely suppressed feeding behavior for up to 3 hours, demonstrating a clear dose-effect relationship