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[2] Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH

In many cases, yes, if it is used and not too often

[60] Low muscle tone (hypotonia) can be a sign of many underlying conditions, including vitamin deficiencies (B1 and other B vitamins), hypothyroidism, carnitine deficiency, creatine deficiency, and methylation issues, as well as genetic conditions (of which there are hundreds)

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Weight gain (especially in the trunk and face), muscle weakness, thinning skin, easily bruising, elevated blood pressure, glucose intolerance, and mood swings are all typical signs of Cushings syndrome (27)