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References 1 AdikeA.DiBaiseJ

Anti-aging mechanism: GHK-Cu upregulates genes involved in tissue repair and downregulates genes associated with inflammation and cancer progression

and de novo synthesis of GSH by cancer cells occurs as follows: GSH is first exported from the cell of origin via transporters known as Multiresistance Drug Proteins (MRPs), which belongs to the ATP binding cassette (ABC)s transporter family and is well-known player in cancer resistance mechanisms (33)

Examination of mouse and human breast tumours revealed that tGSH levels were enriched in the TIF compared to serum (Fig