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You should not take vitamin B12 supplements if you have sensitivities or allergies to B12, cobalt, or any other ingredients in the supplement

Requires careful evaluation are adults with active or historical cancer (growth-promoting compounds require oncology-history review), significant cardiovascular disease, multiple medications requiring interaction screening, or pituitary conditions for growth hormone secretagogues

Vitamin B12 is essential for many important functions in the bodyyet in certain cases, too much of it may be linked to acne breakouts

The most reliable indicator is reduced or absent effects at your expected dose