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10.1007/s12011-017-1044-9 Biol
The specific upstream triggers of each disease (such as A, ischemia and hemorrhage) activate these common downstream pathological processes, which in turn are the direct upstream activators of the core ferroptosis machinery (iron overload, lipid peroxidation and antioxidant system depletion)
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Ferroptosis is an iron-dependent form of regulated cell death characterized by lipid peroxidation and iron metabolism disorders and is closely related to oxidative stress damage in the body[7]
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