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La evidencia clnica es heterognea, pero el encuadre fisiopatolgico resulta coherente en subgrupos

Other medications that may contribute include: Antibiotics , which can disrupt the natural bacteria in your intestines Magnesium supplements or antacids , which loosen stools Certain laxatives or stool softeners , which add to the fluid in the colon The gut microbiome the collection of bacteria in your digestive tract also plays a role

Conversely, waiting more than 30 minutes to eat may increase drug absorption

10.1016/S0140-6736(18)32261-X 222

If you are working with [compounded retatrutide](/products/retatrutide-001), you are handling a lyophilized (freeze-dried) peptide that needs to be mixed with bacteriostatic water before [injection guide](/guides/how-to-inject-glp1-medications-guide)