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Several genes of chromosome 21 are directly implicated in oxidative stress, involving Cu, Zn-SOD (SOD1), ETS2 (ETS Proto-Oncogene 2) transcription factor, stress-inducible factor, protein S100, Down syndrome critical region gene 1 (DSCR1), amyloid precursor protein (APP), the -site APP cleaving enzyme 1 (BACE1) (Antonarakis et al

Microglia diversity in healthy and diseased brain: insights from single-cell omics

20 kg: 55 mL/m 2 (provides 5.5 g/m 2 of sodium phenylacetate and 5.5 g/m 2 of sodium benzoate) IV loading dose, then can follow with maintenance dose, as above

R., Reuter, S

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