This was obviously in the pre-GLP-1 era.
By imitating the action of the natural hormone GLP-1, semaglutide helps regulate blood sugar levels, reduce appetite, and improve metabolic health
Update on the management of diabetic retinopathy: anti-VEGF agents for the prevention of complications and progression of nonproliferative and proliferative retinopathy
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But it creates three immediate nutritional risks: Inadequate protein intake muscle loss alongside fat loss, lowering metabolism long-term Dehydration reduced thirst cues lead to worsening constipation, fatigue, and headaches Nutrient deficiencies smaller portions mean less iron, B12, calcium, and fibre unless meals are planned The STEP-1 clinical trial showed that participants on semaglutide who also followed a structured, reduced-calorie eating pattern lost an average of 14.9% of their body weight over 68 weeks