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According to the Food and Drug Administration (FDA), animal studies suggest it can cause birth defects and an increased risk of pregnancy loss

A cascade mechanism gets initiated leading to the downstream stimulation of chemokine and intracellular adhesion molecule (ICAM) formation following the generation of IL-l and TNF, respectively [185]

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Chang Q, Mao H, Feng J, Rao L, Tang W, Zhang Z, Hu Z