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doi: 10.1016/0891-5849(91)90033-Y 196

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Similarly, mice lacking the anti-inflammatory cytokine interleukin 10 (IL-10 -/- mice) spontaneously develop colitis after weaning whereby onset and severity of inflammation are dependent on the microbiota and the genetic background of mice (40), with the 129/SvEv mouse line being more susceptible than C57BL/6 mice

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