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doi: 10.3390/nu11071437 169

It should be noted, however, that despite subjects with discordant findings on exercise testing having lower resting filling pressures, rates of atrial fibrillation, and fewer structural abnormalities, they exhibited similar severities of exercise impairment

A schematic workflow for this protocol is shown in Figure 2

2 1 JDMM BMI200320152015BMI25BMI22 303402 GLP-12GLP-1GLP-1 GLP-1111GLP-1 GLP-1 GLP-12 GLP-1 GLP-1 2GLP-1 GLP-1 210GLP-14GLP-1 GLP-1 2393GLP-14 GLP-1GLP-1DPP-4 :LiraglutideDPP-42 3827(5,032)129(2,091)24HbA1cHbA1c 0.9mg:LiraglutideDPP-4(:Vildagliptin:Sitagliptin:Linagliptin:Alogliptin:Teneligliptin:Trelagliptin:Omarigliptin) 2:Liraglutide0.9mgDPP-4 1HbA1c7% GLP-1HbA1c1HbA1c7.0%CCPI,100C/HbA1c7.0%SU1.861.10 GLP-1 GLP-1 GLP-1GLP-1GLP-1 BMI 25kg/m257 150mg/dL2200mg/dL0.3mg/10.3mg/0.9mg/ GLP-1 GLP-12 GLP-1212GLP-1371.59kg GLP-1 GLP-1 GLP-1LEADERSUSTAIN-6 24 24 14GLP-1DPP4GLP-1GLP-1GLP-1 GLP-14 2 SU10 UKPDS24,209 SU2,729met3421,13810 Holman RR et al.N Engl J Med 359(15)1577-1589, 2008 21013159242 50% GLP-130 GLP-1 23HbA1c7%1,168 HbA1c7%6Hb1Ac7% Pantalone KM, et al