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Regulation of other signaling pathways In addition to Nrf2 and insulin signaling pathways, lipoic acid was found to target other cell-signaling molecules thereby affecting a variety of cellular processes, including metabolism, stress responses, proliferation, and survival

Key points Understanding of the cellular and molecular mechanisms underlying lupus nephritis (LN) is progressing rapidly, facilitated by new tools for advanced omic analyses

Oxidative stress is a major trigger for platelet activation and aggregation

Recycles antioxidants in the body, playing a vital role in the detoxification process

beta2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis