The likely rationale for this decision is that animal studies have found dietary glucose (the sugar in food and drinks) can suppress GH levels in rats [8], and GH levels in humans are known to peak in the late evening, just before bedtime
Its varied potential mechanisms are thought to include interaction with inducible and/or endothelial nitric oxide-generating systems, by influencing serotonin, dopamine, GABA, and/or opioid metabolism, and/or by directly aiding blood flow, repair, regrowth, angiogenesis, and remodeling
Annual results for height velocity, height velocity SDS, and height SDS are shown in Table 2
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N Engl J Med 1988;319:1557-62