Triple-negative breast cancer (TNBC), the most malignant subtype, is linked to a highly unfavorable prognosis and poor overall survival (OS) rates compared with other subtypes (3)
Sanjurjo, L., Aran, G., Roher, N., Valledor, A
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In preclinical models, MOTS-c has also been shown to help cells tolerate metabolic and oxidative stress, which is part of the basis for interest in its potential role in aging and age-related disease
Subsequently, Th17 cells produced IL-21 through autosecretion, which further amplified the differentiation process [21]
