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Western blot analyses For the in vitro studies, differentiated C2C12 cells were collected at the end of experiments by cell lysis in ice-cold RIPA buffer

doi: 10.1007/s11894-010-0120-5

GSB-106 GSB-106, formally known as hexamethylenediamide bis(N-monosuccinyl-L-seryl-L-lysine), is a dimeric dipeptide mimetic designed to replicate the activity of BDNF loop 4

The oral form uses a SNAC (sodium N-[8-(2-hydroxybenzoyl)amino]caprylate) absorption enhancer to allow GLP-1 passage through the gastric mucosa, achieving approximately 1% bioavailability compared to subcutaneous injection