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Conclusion In conclusion, this study reveals that excessive GSH intake may contribute to chemotherapy resistance in breast cancer patients, identifying high GSH intake as an independent risk factor for tumor recurrence

PLoS ONE 6 , e17706e17706 (2011)

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Its regulation is also different from that of NRF2, which is mainly regulated by N-glycosylase 1 (NGLY1) and DNA loss inducer 1 homolog 2 (DDI2) [13, 14]