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This study, the first of its kind, examines the effects of GLP-1RAs like semaglutide (Ozempic) and compares them with other widely used antihyperglycemic agents

Sirtuins utilize NAD + to catalyze deacetylation and ADP-ribosylation reactions, thereby modulating gene expression, metabolism, and stress resistance in a manner tightly linked to cellular NAD + availability

Foods that May Lower IGF-1 Certain foods and nutrients have also been reported to lower IGF-1, including green tea, lycopene and alcohol

The fix is simple: replace at least a third of daily water intake with electrolyte-enhanced fluids

While most SUSTAIN trials focused on glycaemic control and weight changes, the SUSTAIN-6 cardiovascular outcomes trial specifically evaluated cardiovascular safety