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in molecular genetics in 1995, focusing on gene regulation in yeast

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demonstrated that activation of the nuclear receptor FXR by BAs significantly suppresses ferroptosis by upregulating multiple ferroptosis gatekeepers, including GPX4, FSP1, PPAR, SCD1 and ACSL3 ( Furthermore, studies have confirmed the presence of physiologically relevant concentrations of BAs species in ovarian tissue, along with expression of FXR and BAs transporters ( 4.2.4 Lactic acid bacteria metabolites Lactic acid bacteria produce various metabolites, including 1,3-diaminopropane (DAP), reuterin, and 5-methoxyindoleacetic acid (5-MIAA)

Even in minute quantities, they can trigger severe immune responses in humans, making their detection crucial for injectable products like SLU-PP-332

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