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While our results suggest increasing migraine prevalence and burden with decreasing GABA, it is possible that those who have more severe migraine burden also have shorter times between attacks

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Symptoms of adrenal fatigue may, in some cases, be due to something known as adrenal insufficiency

3 4 5 6 The exact impact is hard to pin down due to the long time scales involved in the development of these diseases, but it is an area of very active research