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You take them daily or twice daily by mouth

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[3] The doses used in these tendon studies typically ranged from 10 to 200 micrograms per kilogram of body weight, administered once daily, which when extrapolated to a 75-kilogram human would suggest a working range of approximately 200 to 500 micrograms per day

For that, the relevant therapy is the one that has been part of menopausal care for decades, and that has had a more complicated clinical history than almost any other intervention in women's medicine

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