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This protective effect offered by THC is thought to be facilitated by the activation of CB 2 Rs, which is elevated in microglia and astrocytes within an inflammatory environment (Benito et al., 2008

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438 Even in the presence of normal blood glucose, insulin resistance is still harmful, and the lack of insulin receptor signaling pathways in renal pedal cells induces a disease state similar to diabetic nephropathy

Whether these rapid responses reflect true biological effects or placebo components remains difficult to distinguish

Jensen SBK et al