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For example, in LGG, higher GLP-1R expression was significantly associated with longer OS (HR = 0.45, p = 1.6125e-05), whereas in lung squamous cell carcinoma (LUSC), elevated GLP-1R expression was correlated with shorter OS (HR = 1.52, p = 2.7740e-03) (Fig

When ghrelin climbs or cortisol remains elevated, the body prefers to hoard fat, especially in areas where it once stashed surplus

Data sources The data for this MR analysis were sourced from the OpenGWAS Project [23, 24]

The risks of stopping GLP-1 medications abruptly include not just weight regain but potential withdrawal-like symptoms including rebound hunger and blood sugar fluctuations

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