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Regarding to immune response, oxaliplatin-treated neurons release significant amounts of pro-inflammatory cytokines, mainly TNF- and IL-6, whereas prostaglandin E2 levels were significantly higher in macrophagues exposed to the platinum compound than in control cells

Melanin is a negatively charged, hydrophobic pigment essential for survival in the host system [140]

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Furthermore, pyruvate carboxylase was identified as a potential NRF2-MafG target gene [72]