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The body stores B12 in the liver, with reserves typically lasting several years

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Changing direction rapidly, stopping suddenly, slowing down while running, landing from a jump incorrectly, and direct contact or collision, such as a football tackle, can also cause injury to the ACL

This is supported by particular changes in the gene expression (i.e., increased Nos1 , Nos2 , and Nos3 expression along with the increased Ptgs2 expression) (Figure 16)