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Oxidative stress arises from factors like intense exercise, environmental exposure, and metabolism

Figure 1 VNS modulates PD pathology through two synergistic pathways: (1) Peripheral (Gut) Effects: Reshapes gut microbiota composition and metabolites ( LPS, SCFAs), reduces intestinal inflammation and -Syn expression, and inhibits -Syn propagation to the CNS via the VN

However, always discuss supplementation with your provider before combining therapies to ensure safety and avoid redundant antioxidant support

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These requirements add to manufacturing costs and complexity