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CHS: Chalcone synthase
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Interestingly, the generation of R-2-HG from glutamine has been proven to occur rapidly in patient-derived chondrosarcoma cell lines harboring endogenous IDH mutations, indicating fundamental metabolic differences between cells that harbor IDH1/2 mutations and those that do not 121
However, around the age of 30, a person's need for glutathione surpasses their body's ability to produce it, largely due to increased exposure to harmful elements and a decrease in the production of necessary enzymes
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