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The series is active in vitro in the low nM range against 12 strains of P

PMID: 31358527 Redox Biol VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity

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All doses require reconstitution from powder using bacteriostatic water, following proper peptide reconstitution protocols

In summary, ferroptosis is closely associated with the pathogenesis of various CCVDs, and with continued research, inhibition of ferroptosis to prevent cardio-cerebrovascular cell death has the potential to be an effective strategy for the treatment of CCVDs