Following the incubation period, cochlear samples are fixed in 4% paraformaldehyde for a minimum of 30 minutes after treatment then permeabilized in 0.5% Triton in PBS (PBST) for 1 hour, followed by overnight incubation at 4 C
Six of the clinical trials involved semaglutide the ingredient used in Novo Nordisk's brands Ozempic and Wegovy and tirzepatide, used for Eli Lilly's Mounjaro and Zepbound
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For example, one trial showed that a GLP-1 drug reduced the risk of cardiovascular death, nonfatal heart attack, and nonfatal stroke by 26 percent in people with type 2 diabetes
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