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Noncompetitive antagonism at the NMDA receptor calcium channel inhibits the effects of glutamate, the major excitatory neurotransmitter in the central nervous system (CNS)

Splitting, chewing, or crushing the tablet also breaks down this barrier, making the drug less effective

The emerging consensus among dental professionals includes several key points: GLP-1 users need more frequent monitoring, salivary health should be assessed at every visit, and cosmetic outcomes should be discussed proactively

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