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In Nixdorff's assessment, the tablet falls somewhat short of the effects achieved by the established GLP-1 injections

This loss of collagen and epithelial stiffness is also suggested to be a cause of other diseases and aging-related complications such as corneal 130 , skin 131 and teeth tissue 132 deteroriation

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Additionally, changes in insulin and insulin-like growth factor-1 (IGF-1) levels associated with improved glycemic control may have complex effects on bone remodeling

Definitive answers are eagerly awaited from ongoing trials like the FOCUS study (NCT03811561), which is specifically designed to clarify the long-term impact of semaglutide on diabetic eye disease [96]