Interestingly, no marked food intake reduction effect of Ex was observed in S2 (4 to 5 h after treatment), and, surprisingly, the previously observed successive positive contrast in food intake in S2 also persisted under Ex treatment
10.1172/JCI75276 43 SeinoS.TakahashiH.FujimotoW.ShibasakiT
p , GGsTop aliquots (25 mg/mL in H 2 O) were kept at room temperature for the indicated number of days, after which their inhibitory potency was assessed using an in vitro activity assay with mouse kidney lysates (n = 3 technical replicates)
For these reasons, GLP-1 analogues have been FDA-approved for treatment of obesity and diabetes, Dr
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