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Glutamine enters the cell via the ASCT2 / SLC1A5 amino acid transporter and is converted to glutamate in the mitochondria through a glutaminase-catalyzed deamination reaction (GLS)

In addition, no protective benefits were seen in patients over the age of 80 taking the drugs

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FDA-approved indications require either a BMI of 30+ or BMI of 27+ with comorbidities for weight management, or a type 2 diabetes diagnosis for the diabetes formulations