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The responsible clinical approach is to titrate slowly, evaluate response at each stage with monitoring, and stop increasing when results are adequate rather than when the theoretical maximum has been reached

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Abbreviations NP: Nanoparticles Th2 cells: T helper 2 cells IL: Interleukins CS: Chitosan PLGA : Poly D, L-lactic-co-glycolic acid PAMAM : Poly(amidoamine) PHPMA : Poly(N-(2-hydroxypropyl) methacrylamide References Hammad H, Lambrecht BN

Tomljenovic & Shaw (2011) state that substantially high level of Al in the brain is associated with Alzheimer Disease, a well-known neurodegenerative disease

The combination produces a synergistic research signal larger than either compound alone at equivalent total doses