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A 2025 systematic review published in the Orthopaedic Journal of Sports Medicine examined 36 studies on BPC-157 published between 1993 and 2024

Morphine reward in dopamine-deficient mice

DOI: 10.1016/S0928-4257(97)89480-6

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Abstract The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders