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FIGURE 2 6 Conclusion and future perspectives Therapeutic approaches to address oxidative stress typically involve upregulating antioxidant signals such as NRF2, administering exogenous antioxidants, supplementing trace elements or nutrients, and implementing environmental interventions ( de novo GSH synthesis but also exhibits independent antioxidant effects

Oxidant mechanisms in renal injury and disease

Cystine is readily imported into cells where it is converted to cysteine, the limiting precursor for GSH formation (Yin et al., 2016)

Development of eDNA techniques for risk evaluation, not only for liver flukes but also for intermediate hosts, especially snails

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