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Strengths and limitations The selection of OI as a comparison group is important as it is different from healthy control, or more specifically a non-injury comparison group

James ND, Tannock I, NDow J, Feng F, Gillessen S, Ali SA, Trujillo B, Al-Lazikani B, Attard G, Bray F, Comprat E, Eeles R, Fatiregun O, Grist E, Halabi S, Haran , Herchenhorn D, Hofman M, Jalloh M, Loeb S, MacNair A, Mahal B, Mendes L, Moghul M, Moore C, Morgans A, Morris M, Murphy D, Murthy V, Nguyen PL, Padhani A, Parker C, Rush H, Sculpher M, Soule H, Sydes MR, Tilki D, Tunariu N, Villanti P, Xie LP

People taking certain medications are also at higher risk

Pregnant or breastfeeding women should also consult their healthcare provider before starting treatment

Plaque rupture exposes pro-thrombotic material to the bloodstream, triggering the formation of blood clots that can occlude arteries and lead to acute cardiovascular events such as myocardial infarction and stroke [74]