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If nausea or vomiting is severe or persistent, temporarily maintaining the current dose for an additional 4 weeks before escalating, or even reducing to the previous tolerated dose, may be warrantedbut any dose modifications must be directed by the prescribing healthcare provider
What makes it feel overwhelming is the number of variables, different concentrations, different syringe sizes, half-unit measurements, and the real consequence of getting it wrong
The One-Agent-at-a-Time Principle Incretin compounds are always introduced one at a time and titrated in steps typically starting low and increasing every four weeks specifically so tolerability and response can be attributed to a single variable