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Avoid products making physiological promises unsupported by known biochemistry (e.g., increases melanin by X%)

This potential risk was increased if the siblings had the genetic predisposition (specially the alleles DQB1*0302/*0201 of high susceptibility) which increased the possibility of developing autoantibodies

But 19 years after Prozac entered the market, there was an article in CNS Drugs (2006)

Over time, this results in reduced production of thyroid hormonesprimarily thyroxine (T4) and triiodothyronine (T3)which are essential for regulating metabolism, energy production, and numerous bodily functions

[DOI] [PMC free article] [PubMed] [Google Scholar] Gutscher M, Sobotta MC, Wabnitz GH, Ballikaya S, Meyer AJ, Samstag Y, Dick TP