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Practical considerations and rationale for glucagon-like peptide-1 receptor agonist plus sodium-dependent glucose cotransporter-2 inhibitor combination therapy in type 2 diabetes

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Although the increased yield of adenosine triphosphate (ATP), a common form of cellular energy currency, was metabolically beneficial, the tradeoff between efficiency and risk to the metabolic machinery grew more prominent

Symptoms of the patients is diverse from no symptom to severe pain and dysphasia

The researchers concluded that the drop in cAMP levels observed in some cells likely resulted from cAMP degradation