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In pancreatic tissue, GLP-1 receptor agonists enhance glucose-dependent insulin secretion and suppress inappropriate glucagon release, thereby improving glycemic control without significantly increasing hypoglycemia risk

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doi:10.1007/s00264-020-04610-0 Viecelli AK, Polkinghorne KR, Pascoe EM, et al

However, the exact way NNMT works still needs more exploration, and further studies are needed to fully understand and develop treatments focused on NNMT