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For the FP competition assay, the unlabelled compounds (from 50-mM DMSO stocks) were first dispensed in duplicate into wells of a Proxiplate 384 F Plus plate using an Echo 550 acoustic liquid handler to give a 13-point concentration range from 0.2 to 500 M

Carbone JW, Pasiakos SM

In terms of dosage, again, the key is often, daily at least (some of our readers inject twice a day)

There simply arent enough production lines to flex capacity quickly