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A double-blind, randomized phase 2 study comparing various doses (1, 5, 10, 15 mg) of once weekly tirzepatide, dulaglutide (1.5 mg) and placebo, in patients with T2DM, showed tirzepatide was superior on weight loss and glucose-lowering compared to both dulaglutide and placebo [52]

He was recently awarded the prestigious feac fellowship

In the intestine and brain, PC1 converts proglucagon to the incretin hormones, glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2)

Transcriptional activation of G6PD in response to oxidative stress is carried out by the transcription factor, NRF2 (nuclear factor erythroid 2related factor 2)

The new JAMA Network study also contradicts some previous findings that semaglutide use does not lead to higher risks of suicidal thoughts