120-122 Postmarket reportswhich may overestimate side effectshave noted renal impairment upon initiation and dose escalation of GLP-1s, which appears due to volume depletion resulting from dehydration caused by nausea and vomiting
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receiving research grants from Chief Scientist Office, Diabetes UK, European Commission, IQVIA, Juvenile Diabetes Research Foundation and Medical Research Council
Common Physical Side Effects While GLP-1 medications are generally well-tolerated, their impact on the metabolic and gastrointestinal systems can cause several common side effects: Nausea: The most frequent side effect, typically occurring during initial treatment or dosage increases
Changes in body composition, energy levels, and muscle tone typically require 8-12 weeks of consistent use, though individual response varies based on dosing, lifestyle, and baseline growth hormone levels