Coll et al., 2007
In the central nervous system (CNS), GLP-1 and GLP-1R agonists are diffused into the cerebrospinal fluid (CSF) and the brain as demonstrated in rodent models (Wang et al., 2015), and increased GLP-1 concentration in the brain is thought to influence brain function in the hippocampus (Kastin et al., 2002
Cannabis While no pre-clinical or mechanistic study has considered GLP-1RAs for cannabis misuse so far, a large epidemiological investigation has recently noted an association between semaglutide use and fewer cannabis-use disorders in both patients with T2DM ( N = 596,045) and patients with obesity ( N = 85,223) over a 1-year follow-up 114
At Reclaim Therapy, we specialize in trauma-informed therapy for eating disorders, body image concerns, and complex trauma
My role is to serve as your medical partner, customizing a plan that may include FDA-approved anti-obesity medications such as semaglutide (Wegovy) and tirzepatide (Zepbound)
