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10.1093/brain/awx024 13 AsensiM.SastreJ.PallardoF

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Plasma concentrations drop from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60 a 60% reduction

For researchers concerned about cardiovascular risk, practical strategies to minimize TMAO production include supporting a healthy gut microbiome through prebiotic and probiotic use, monitoring TMAO levels if testing is available, and keeping total levocarnitine exposure within studied safety ranges