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Patients with nutritional compromise face increased risk for systemic inflammatory response syndrome (SIRS) with IV administration
These include regulating the hosts immune system (triggering T cell differentiation), activating antigen-presenting cells (APCs) through an effect on Toll-like receptors (TLRs) or NOD-like receptors (NLRs), promoting the citrullination of peptides by enzymatic action, antigenic mimicry, and increasing the intestinal mucosal permeability (Horta-Baas et al., 2017
doi: 10.1124/dmd.117.076034 16 ChenY
J Clin Epidemiol
Every particle your body filters out uses up a little glutathione in the process
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