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Encapsulation is extensively utilized in nutritional supplements to safeguard probiotic cells during industrial processing and long-term storage, as well as to protect them from the harsh physicochemical conditions encountered in the GI tract

Recent studies have continued to provide new evidence strongly indicating that the gut microbiota may be a key link in the pathogenesis of NAFLD and its progression to NASH and cirrhosis

Building upon this newly identified target-apoptosis axis, our findings extend the established pharmacological profile of palmatine , an isoquinoline alkaloid from Coptis chinensis and Phellodendron chinense with documented efficacy in MASLD 80

the liver cells mitochondria are particularly vulnerable to damage

These changes lead to reduced gene expression through alterations in histone acetylation and DNA methylation [126, 127]