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The article says common effects such as nausea, mild appetite suppression and constipation often improve over two to three weeks, and that if the level is tolerated and progress stalls, providers may move to 7.5 mg or 10 mg

Neurobiol Dis 33:133142 Jayakumar AR, Panickar KS, Murthy C, Norenberg MD (2006) Oxidative stress and mitogen-activated protein kinase phosphorylation mediate ammonia induced cell swelling and glutamate uptake inhibition in cultured astrocytes