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Understand the difference between insoluble versus soluble fiber and more in this article from GobyMeds

Effect of Bromocriptine in Improving Non-Alcoholic Fatty Liver Disease in Obese Animal Model of Type 2 Diabetes

The two research-favored windows are pre-bed (stacking onto the natural overnight GH surge) and fasted morning

Moreover, deficiencies or dysfunctions in transcobalamin II, which is essential for transporting B12 in the bloodstream, can further impact its bioavailability

So there was some weight regain, about 5.7 pounds on average, but dramatically less than the 20 pounds regained by the placebo group